HIV in older people

April 30th, 2010 by zheng No comments »

Gary Pratt et.al reviewed HIV in older people last year and documented that there were several reasons why older people were at risk.

1. The few HIV prevention campaigns that do exist do not target the elderly.
2. Older people may not consider themselves at risk of HIV infection.
3. Health care providers may not consider the diagnosis in older patients and therefore may not undertake HIV testing or may attribute symptoms of HIV to ‘normal ageing’.
4. Despite the stereotypes, many older people lead sexually active lives. Studies of sexual activity in people aged over 50 showed that 81.5% were involved in one or more sexual relationships including sex with prostitutes,and a national US survey suggested that only a small minority of people over 70 consistently used condoms. Older women may be especially at risk because age-related vaginal thinning and dryness can cause tears in the vaginal wall.
5. The increase in foreign travel makes access to countries with thriving sex industries easier.
6. The introduction and usage of potency drugs has extended the sex lives of many elderly males.
7. Injection drug usage, despite our misconceptions, is a contributor to HIV transmission in older people. In the USA, injection drug use accounts for more than 16% of AIDS cases in those aged 50 or over.
8. The stigma of HIV may be perceived to be greater in the elderly population leading them to hide their diagnosis or avoid testing.

The paper is a very good review in Age and Aging. My colleague – Ruth Smith present some important findings at the joint conference of the British HIV Association (BHIVA) and the British Association for Sexual Health and HIV (BASHH) last week. In the United Kingdom, one in twelve HIV diagnoses are of a person over the age of 50. Whilst rates of late diagnosis are high in older adults, just under half of these diagnoses are thought to be of an infection that was acquired when the person was over the age of 50.

making sense of randomised trials

April 29th, 2010 by zheng No comments »

in NAM’s HIV treatment update April 2010, there is a short article on how to understand clinical randomised trials. it summarised key concepts used and provide a brief explanation for each of them. Nice and handy.

The article will be available at http://www.aidsmap.com/cms1061207.asp after a few weeks.

China lifts travel ban against people with HIV

April 28th, 2010 by zheng No comments »

Never too late.

It’s a good thing though. We need to bring people together to remove stigma related to HIV. China authority said this change won’t have a significant impact on the HIV epidemic in China. Yes and No. In China, the most serious problem is internal migration. It benefits the economic development a lot but inevitably causes problems such as prostitution, education, transportation, pollution etc etc. Most international population movement is actually emigration instead of immigration. Because of the small proportion of HIV positive individuals of the whole immigration population, it probably won’t make a big difference. However, in an other hand, several factors may effect the epidemic, for example, short-term visitors are likely to engage in risky behaviour, condom use is still not very common in China despite of free provision, many young girls favour foreigners for various reasons, HIV testing requests a lot a lot more efforts to promote, Chinese hold very different attitudes toward testing, treatment, sex and HIV compared to Britain and Americans. ….

If let the whole nation vote, the proposal might wouldn’t get passed. Thanks we are not a democracy country! pros and cons.

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the following informaiton is from http://news.yahoo.com/s/ap/20100428/ap_on_re_as/as_china_aids

China lifts travel ban against people with HIV/中国不再禁止国外艾滋病等患者入境.

BEIJING – China has scrapped a 20-year travel ban that barred people with HIV and AIDS from entering the country, just days ahead of the opening of the Shanghai Expo, which hopes to welcome millions of overseas visitors.

The decision announced by China’s Cabinet, the State Council, follows similar moves by the United States and South Korea to eliminate travel restrictions for people with the HIV virus. Both lifted their bans on visitors with HIV on Jan. 1.

China’s ban had been launched based on “limited knowledge” of HIV at the time and had proven inconvenient for the country when hosting international events, the official Xinhua News Agency quoted the Cabinet as saying. The Shanghai Expo begins Saturday and runs for six months.

The State Council said in a statement posted to its website late Tuesday that the government passed amendments on April 19, revising the Border Quarantine Law as well as China’s Law on Control of the Entry and Exit of Aliens. The changes were effective immediately.

The move also includes scrapping entry restrictions for people with leprosy and sexually transmitted diseases.

The State Council said that the government realized such restrictions had limited effect on preventing and controlling the spread of diseases in the country, according to Xinhua. The Cabinet did not immediately respond to faxed questions.

AIDS was the top killer among infectious diseases in China for the first time in 2008, a fact that may reflect improved reporting of HIV/AIDS statistics in recent years. Despite greater openness, the government remains sensitive about the disease, regularly cracking down on activists and patients who seek more support and rights.

Government statistics show that by the end of October 2009, the number of Chinese confirmed to be living with HIV-AIDS was 319,877, up from 264,302 in 2008 and 135,630 in 2005. But Health Minister Chen Zhu has said the actual level of infections is probably near 740,000.

U.N. Secretary-General Ban Ki-moon welcomed China’s decision and urged other countries that still bar people with HIV to change their laws as soon as possible. “Punitive policies and practices only hamper the global AIDS response,” he said in a statement.

reading notes 16042010

April 16th, 2010 by zheng No comments »

In the UK, the Gay Men’s Sex Survey in 2005 found that only 3% of the whole sample had used methamphetamin and that only 0.3% were frequent users of the drug.
(Methamphetamin – meth, crystal, ice, tina, Christine, yaa baa, Nazi speed is a chemically altered version of amphetamin. It was banned in the UK in 1964 and the USA in 1971).

News from the 17th. conference on retroviruses and opportunistic infections
San Francisco has promoted HIV testing so well that only one in seven people with HIV are undiagnosed.

In South Africa, nearly a quarter of patients eligible for HIV therapy died while on the waiting list.
(ref: Montaner j et al. Association of expended HAART coverage with a decrease in new |HIV diagoses, particularly among injection drug users)

Researchers from the DAART trial in Uganda and Zimbabwe found that within a year of starting treatment, 78% of patients had not achieved a CD4 count over 350 cell/mm3 and nearly half had not reached 200.
(ref: Munderi P et al. Immune restoration over 5 years on ART among patients initiating treatment with advanced immune deficiency in the DART trial in Uganda and Zimbabwe)

HIV transmission in long-term hetrosexual relationships could not be prevented by treating herpes. The rate of transimission from a HIV-positive patner was reduced from 2.25% to 0.39% a year when they started treatment.

Partners with CD4 counts under 200 cells/mm3 were five times more likely to transmit HIV than others.